SUMMARY
Todd DeWald conducted a real-world comparison of the OM System 100-400mm and 50-200mm f/2.8 lenses for Micro Four Thirds wildlife photography. The 50-200mm f/2.8 demonstrated superior autofocus speed, a higher keeper rate, and sharper images, even when paired with teleconverters to match the 100-400mm's reach. However, the 100-400mm offers the convenience of a single lens with a wide zoom range (200-800mm equivalent) without needing accessory teleconverters, though its variable aperture requires higher ISO or slower shutter speeds in low light. The 50-200mm is more expensive and requires carrying teleconverters for extended reach.
TAKEAWAYS
The 50-200mm f/2.8 lens generally produced sharper images and faster autofocus than the 100-400mm.
The 100-400mm lens offers convenience with its integrated 200-800mm equivalent zoom range.
The 50-200mm f/2.8, especially with teleconverters, outperformed the 100-400mm in some sharpness tests.
The 100-400mm's variable aperture can necessitate higher ISO or slower shutter speeds in low light.